Archive for the ‘Therabreath Plus’ Category

The bonus pak special starts NOW!

Wednesday, February 3rd, 2010

Hello readers –

The World Series, New Years Eve, the First Day of Spring, your Birthday … these are things we spend all year waiting for. We now add one more event to this list – the TheraBreath semi-annual BONUS PAK SALE! (While it’s not as exciting as New Years Eve, it will definitely save you more money and be better for your mouth)

During this special event, get our BONUS PAK premium oral care products at savings
UP TO 60% OFF* their individual price.

CLICK HERE to check out our BIGGEST SALE OF THE YEAR

This is the perfect time to stock up on Dr.Katz products: TheraBreath Oral Rinse and Paste guaranteed to stop all bad breath, Aktiv K-12 Probiotics that the health magazines are buzzing about, PerioTherapy products for eliminating gum disease, TheraBrite teeth whitening products, even the WaterPik Professional Sensonic Toothbrush – the best sonic toothbrush on the market! There is no limit to how much you can save.

Want an even better deal? No problem.
We’ll also throw in FREE SHIPPING on every BONUS PAK SALE order.

This is absolutely, positively our BIGGEST SALE OF THE YEAR. Our regular customers who are familiar with the BONUS PAK SALE are already skipping the rest of this email and busy placing their orders. For those that are not as familiar with this most special of specials, let me break it down for you:

  1. Order one of our BONUS PAKS and save 30% or more off our regular, individual item retail prices.
  2. Choose $100 or more worth of additional Dr. Katz Products ABSOLUTELY FREE for each and every BONUS PAK you order. Choose a pack of our most popular products, or pick your favorite items. You make the call.
  3. Get FREE SHIPPING on everything you ordered, delivered right to your door.

That’s all there is to it. Spend about $120, get about $170 in free products. Spend a lot more, save a lot more. No hidden fees. No tricks. Nothing else to try, buy, or cancel later. This is, hands down, the best offer we make every year. But don’t wait to take advantage of it. Once the BONUS PAKS are gone, this deal is done. And you will have to wait until next year to save this much money.

CLICK HERE to check out our BIGGEST SALE OF THE YEAR

Want more convincing? Here are some numbers for you:

Buy ‘Bonus Pak A’ (Reg: $166, Pak Price: $120)

  • 12 TheraBreath Rinses
  • 4 TheraBreath Pastes
  • Tongue Cleaner
  • Toothbrush

PLUS Choose your Bonus Products (Reg: $94.50, Pak Price: FREE)

  • For example:
  • 6 TheraBreath Oral Rinses
  • 3 TheraBreath Toothpastes

Including shipping, you would typically spend $280 on these items if purchased individually. During this sale, you will get all of them for only $120. That’s a 60% savings. If you have been waiting to re-order your favorite TheraBreath, TheraBrite, and PerioTherapy items, your wait is over. The time to place that order is now.

CLICK HERE to check out our BIGGEST SALE OF THE YEAR

Think this is a great deal? Have a friend who could really use some of our products?
Tell them!

Want to order by PHONE? Call us at (800) 97-FRESH and mention your savings code : BP10EM1


*Savings are calculated based on the total value of the received package, including the $100 or more in free bonus items.

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Another Bad Breath Spray?

Thursday, June 18th, 2009

If you are like me, then you’re probably thinking “Not another breath spray – isn’t rinsing and brushing enough?”

It’s a valid question…and one that I think I’ve tried to answer before, but I don’t mind doing it again.

Let me start by saying this – bad breath is the odor of the volatile sulfur compounds (VSCs) that are created from the anaerobic bacteria that live in your mouth, between your teeth, beneath the surface of your tongue, in the back of your throat, and in your tonsils (if they exist).

breath spraySee the picture to the left…. reaching your mouth, teeth, and front of your tongue in regions D, E, and F is simple – tens of thousands of you do it every day with our TheraBreath Oral Rinses and Toothpastes. But what about the production of odors farther back (Regions A, B, and C) – in the very back of your tongue, deep in your throat or in your tonsils?

When you gargle with an oral rinse (mouthwash) – most of time it can be very difficult to reach way down deep in your throat. Many of my patients find that a ‘Gag Reflex’ kicks in (this happens automatically in most people when something touches a sensitive area in the back of your throat and tongue). So what can you do? To stop bad breath you MUST neutralize the sulfur compounds that have been created by the anaerobic bacteria that live in deep recesses of your throat and tongue.

In response to this exact concern, I’ve created a breath spray that addresses this problem. TheraBreath PLUS Extinguisher Breath Spray has a unique 7.5cm long, swiveling, extended head which holds down the tongue and sprays the potent Therabreath PLUS formula directly on the bacterial breeding ground located in the back of your tongue and throat. It’s the only patented extra strength formula that can literally reach the part of your throat and tongue that no other formula can touch!

Many of you have told me that during your first clinical appointment, you’ve always felt something stuck in your throat – and you’ve attributed that uncomfortable feeling to your breath and taste disorder. This spray was designed to solve that problem.

Please remember that for chronic conditions, the only way to prevent the anaerobic bacteria from creating VSC’s is through daily use of an oxygenating line of products such as TheraBreath Oral Rinse and Toothgel (now at Albertsons, SavOn, Jewel, Osco, and Acme). For specific instructions on how to do this, see the Instructions of Use.

It’s especially useful for patients with:

  1. Chronic bad breath who want extra relief throughout the day
  2. Occasional (situational) breath or taste disorder, who want instant relief without an overbearing strong minty taste or smell
  3. Dry mouth sufferers, whose tongue tends to become extra sticky as the day goes on

TheraBreath PLUS Extinguisher Spray is small enough to carry in your pocket, purse, or briefcase, so that you can even use it before or after your favorite garlic dish. I hope you can now see how a breath spray (especially one that actually reaches the source of bad breath) can help you regain your confidence.

Click Here to Receive Free Shipping
on a 3-pak of ‘Extinguisher’ Breath Spray

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Zinc in Mouthwash Can Help Prevent Bad Breath

Wednesday, June 3rd, 2009

Note from Dr. Katz: The scientific studies which follow will help explain why TheraBreath PLUS Oral Rinse, in addition to a higher concentration of OXYD-8, also contains zinc gluconate. Briefly, science has shown that adding zinc gluconate helps to eliminate sour/bitter/metallic tastes and also aids in reducing tartar buildup. The stabilized chlorine dioxide component (OXYD-8) in TheraBreath PLUS Oral Rinse is utilized to eliminate oral malodor, while tea tree oil assists as a natural anti-microbial.

 


Biofactors 2000;12(1-4):65-70

Zinc deficiency and taste dysfunction; contribution of carbonic anhydrase, a zinc-metalloenzyme, to normal taste sensation.

by Komai M, Goto T, Suzuki H, Takeda T, Furukawa Y.

Division of Life Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan. mkomai@biochem.tohoku.ac.jp

The present study was designed to clarify the effect of zinc deficiency on sodium chloride preference, the lingual trigeminal and taste nerves transduction, and carbonic anhydrase (CA) activity of the tongue surface and salivary gland. Male SD rats, 4 weeks old, were divided into four groups, and fed zinc-deficient (Zn-Def), low-zinc (Low-Zn), and zinc-sufficient diets with free access (Zn-Suf) and pair-feeding (Pair-fed). After taking part in the preference tests for 42 days, the rats were provided for the chorda tympani and lingual trigeminal nerves recordings, then finally sacrificed and the tongue and submandibular gland excised to measure CA activity. Sodium chloride preference increased only after 4 days of the feeding of zinc-deficient and low-zinc diets, which means that the taste abnormality appears abruptly in zinc deficieny and even though in marginal zinc deficiency. Reduced CA activities of the taste-related tissues in zinc-deficient group paralleled well with the decreased taste and lingual trigeminal nerves sensitivities.


Effect of Different Mouthrinses on Morning Breath.

by van Steenberghe D, Avontroodt P, Peeters W, Pauwels M, Coucke W, Lijnen A, Quirynen M.

Department of Periodontology, Oral Pathology and Maxillo-Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Belgium.

BACKGROUND: Morning breath odor is an often-encountered complaint. This double-blind, crossover, randomized study aimed to examine the bad breath-inhibiting effect of 3 commercially available mouthrinses on morning halitosis during an experimental period of 12 days without mechanical plaque control.

METHODS: Twelve medical students with a healthy periodontium refrained from all means of mechanical plaque control during 3 experimental periods of 12 days (with intervening washout periods of at least 3 weeks). A professional oral cleaning preceded each period. During each experimental period, as the only oral hygiene measure allowed, the students rinsed twice a day with one of the following formulations in a randomized order: CHX-Alc (a 0.2% chlorhexidine [CHX] solution); CHX-NaF (CHX 0.12% plus sodium fluoride 0.05%); or CHX-CPC-Zn (CHX 0.05% plus cetylpyridinium chloride 0.05% plus zinc lactate 0.14%).

After 12 days, morning breath was scored via volatile sulfur compound (VSC) level measurements of the mouth air and organoleptic ratings of the mouth air, the expired air, and a scraping of the tongue coating. At the 12-day visit, a questionnaire (subjective ratings) was completed and samples taken from both the tongue coating and the saliva for anaerobic and aerobic culturing and vitality staining. The de novo supragingival plaque formation was also recorded. All parameters were correlated with the baseline registrations.

RESULTS: Although oral hygiene during the 3 experimental periods was limited to oral rinses, bad breath parameters systematically improved, with the exception of a slight increase in VSC levels while using CHX-Alc, a finding which was associated with the direct influence of the CHX on the sulfide monitor. The oral microbial load after the use of CHX-NaF remained unchanged, while for the CHX-Alc and CHX-CPC-Zn, significant reductions in both aerobic and anaerobic colony forming units (CFU)/ml were noticed in comparison with baseline data for both tongue coating and saliva samples. The composition of microflora, on the other hand, did not reveal significant changes. The supragingival plaque formation was inhibited, in descending order, by CHX-Alc, CHX-CPC-Zn, and CHX-NaF. The subjective scores for the rinses indicated a higher appreciation for CHX-CPC-Alc and CHX-NaF because of a better taste and fewer side effects. CONCLUSIONS: The results of this study demonstrate that morning halitosis can be successfully reduced via daily use of mouthrinses. CHX-Alc and CHX-CPC-Zn mouthrinses result in a significant reduction of the microbial load of tongue and saliva.

Publication Types:

· Clinical Trial

· Randomized Controlled Trial


PMID: 11577950 [PubMed – indexed for MEDLINE]

J Clin Periodontol 1996 May;23(5):465-70

The effect of mouthrinses containing zinc and triclosan on plaque accumulation, development of gingivitis and formation of calculus in a 28-week clinical test.

by Schaeken MJ, Van der Hoeven JS, Saxton CA, Cummins D.

Department of Periodontology and Preventive Dentistry, University of Nijmegan, The Netherlands.

Experimental mouthrinses containing 0.4% zinc sulphate and 0.15% triclosan, which differed in base formulations were compared to a commercially available non-active control mouthrinse. Following baseline clinical examinations for plaque, gingival bleeding and calculus, the volunteers were provided with a dental prophylaxis and given oral hygiene instruction, stratified into 3 groups and given 1 of 3 mouthrinses.

Further clinical assessments were performed after 4, 16 and 28 weeks. Salivary mutans streptococci were also monitored during the study. At 4 weeks, plaque and calculus scores in all groups were low compared to baseline. During the remainder of the study, these improvements were not maintained and both plaque and calculus levels increased in all groups. Plaque was significantly lower (P < 0.05) than in the control at all time points. Calculus was significantly lower (P < 0.05) than in the control at all time points. Calculus was significantly lower at week 28 for experimental mouthrinse group 2. Gingival bleeding also decreased in the initial 4 weeks but increased thereafter in the control group. In contrast, gingival bleeding was significantly (P < 0.05) lower in the two experimental groups than in the control group. No significant changes in mutans streptococci were observed.


Ann Pharmacother 1996 Feb;30(2):186-7

Zinc Deficiency and Taste Disorders.

by Heyneman CA.

Idaho Drug Information Center, Idaho State University, Pocatello 83209, USA.

Elemental zinc supplementation in daily dosages of 25-100 mg po appears to be an efficacious treatment for taste dysfunction secondary to zinc depletion. Insufficient evidence is available to determine the efficacy of zinc supplementation for the treatment of hypogeusia or dysgeusia secondary to drug therapy or medical conditions that do not involve low serum zinc concentrations.


Ther Umsch 1995 Nov;52(11):732-7

[Article in German] Huttenbrink KB.

Klinik und Poliklinik fur Hals-Nasen-Ohren-Heilkunde der Medizinischen Fakultat Carl Gustav Carus, Technischen Universitat Dresden.

Disorders of olfaction and taste are infrequent, but a complete loss of smell or taste reduces the quality of life significantly. The sensitivity of human olfaction is remarkable, even for specific stimuli: Just a few molecules are enough to induce the correct identification of sterilised and ultraheated milk.

Olfaction and taste are called ‘chemical senses’ because in both cases the adequate stimulus consists of molecules that bind to receptors of the sensory cells. The perceptions of smell and taste are often combined. Taste differentiates only four qualities: sweet, sour, salty, and bitter. The typical flavor of food or drink is detected by olfaction. Disturbances of olfaction can be due to respiratory disorders such as nasal polyps, a deviation of the nasal septum or chronic sinusitis. Such conditions can reduce airflow through the olfactory cleft at the roof of the nasal cavity. They can be corrected by modern endoscopic surgery of the nose.

Epithelial disorders involving the sensory cells are most often caused by viral infections (influenza-anosmia) or toxic destruction of the sensory epithelium (solvents or gases). Epithelial disorders can be cured only rarely by any treatment. Corticosteroids, zinc, and vitamin A are tried frequently. Neural disorders occur after frontobasal trauma and during neurological diseases such as Parkinson’s or Alzheimer’s disease. Disorders of olfaction can be an early sign of such neurological diseases and sophisticated examination of this sense can contribute to their early diagnosis. However, no specific treatments have yet been identified. Disorders of taste can be due to toxic, chemical or inflammatory damage to the sensory cells of the tongue.


Indian J Physiol Pharmacol 1993 Oct;37(4):318-22

Zinc Taste Test in Pregnant Women and its Correlation with Serum Zinc Level.

by Garg HK, Singal KC, Arshad Z.

Department of Pharmacology, J. N. Medical College, A.M.U., Aligarh.

Pregnant women in different trimesters of pregnancy were divided into control (n = 58) and study (n = 104) groups. Study group subjects were given 45 mg zinc/p.o./day as 200 mg ‘zinc sulphate tablets from the day of reporting till term. Body zinc status was clinically assessed by ‘zinc taste test’. Blood samples were drawn at the same time and serum zinc levels measured. Zinc taste test scores decreased with advancement of pregnancy (P < 0.05) and increased significantly following zinc administration (P < 0.05).

Serum zinc level declined significantly with advancement of pregnancy (P < 0.001). Following zinc administration, serum zinc level increased significantly (P < 0.001). Accuracy of zinc taste test in individual cases ranged between 70 and 100 percent. On the whole, zinc taste test was well correlated with serum zinc level, and provides a fair idea of zinc deficiency.


Nutrition 1993 May-Jun;9(3):218-24

Zinc deficiency in elderly patients.

by AS, Fitzgerald JT, Hess JW, Kaplan J, Pelen F, Dardenne M. – Department of Internal Medicine, Wayne State University School of Medicine, Detroit, MI.

Zinc is needed for growth and development, DNA synthesis, neurosensory functions, and cell-mediated immunity. Although zinc intake is reduced in elderly people, its deficiency and effects on cell-mediated immunity of the elderly have not been established. Subjects enrolled in “A Model Health Promotion and Intervention Program for Urban Middle Aged and Elderly Americans” were assessed for nutrition and zinc status. One hundred eighty healthy subjects were randomly selected for the study. Their mean dietary zinc intake was 9.06 mg/day, whereas the recommended dietary allowance is 15 mg/day. Plasma zinc was normal, but zinc in granulocytes and lymphocytes were decreased compared with younger control subjects. Of 118 elderly subjects in whom zinc levels in both granulocytes and lymphocytes were available, 36 had deficient levels.

Plasma copper was increased, and interleukin 1 (IL-1) production was significantly decreased. Reduced response to the skin-test antigen panel and decreased taste acuity were observed. Thirteen elderly zinc-deficient subjects were supplemented with zinc, and various variables were assessed before and after zinc supplementation. Zinc supplementation corrected zinc deficiency and normalized plasma copper levels. Serum thymulin activity, IL-1 production, and lymphocyte ecto-5′-nucleotidase increased significantly after supplementation. Improvement in response to skin-test antigens and taste acuity was observed after zinc supplementation. A mild zinc deficiency appears to be a significant clinical problem in free-living elderly people.

 


Arch Otolaryngol Head Neck Surg 1991 May;117(5):519-28

Smell and taste disorders, a study of 750 patients from the University of Pennsylvania Smell and Taste Center.

Deems DA, Doty RL, Settle RG, Moore-Gillon V, Shaman P, Mester AF, Kimmelman CP, Brightman VJ, Snow JB Jr. – Department of Otorhinolaryngology and Human Communication, School of Medicine, University of Pennsylvania, Philadelphia.

Smell and taste disorders are common in the general population, yet little is known about their nature or cause. This article describes a study of 750 patients with complaints of abnormal smell or taste perception from the University of Pennsylvania Smell and Taste Center, Philadelphia. Major findings suggest that: chemosensory dysfunction influences quality of life; complaints of taste loss usually reflect loss of smell function; upper respiratory infection, head trauma, and chronic nasal and paranasal sinus disease are the most common causes of the diminution of the sense of smell, with head trauma having the greatest loss; depression frequently accompanies chemosensory distortion; low body weight accompanies burning mouth syndrome; estrogens protect against loss of the sense of smell in postmenopausal women; zinc therapy may provide no benefit to patients with chemosensory dysfunction; and thyroid hormone function is associated with oral sensory distortion. The findings are discussed in relation to management of patients with chemosensory disturbances.


J Periodontol 1990 Jun;61(6):352-8

Clinical efficacy of a dentifrice and oral rinse containing sanguinaria extract and zinc chloride during 6 months of use.

Harper DS, Mueller LJ, Fine JB, Gordon J, Laster LL. – Fairleigh-Dickinson University, Oral Health Research Center, Hackensack, NJ.

The efficacy of combined use of toothpaste and oral rinse containing sanguinaria extract and zinc chloride was compared to placebo products in a 6-month clinical trial. Sixty subjects with moderate levels of plaque and gingivitis were randomly assigned to active and placebo groups. Noninvasive measures of plaque and gingivitis were assessed at baseline and at 2, 6, 8, 14, 20, and 28 weeks. Bleeding on probing was measured at baseline and 6, 14, and 28 weeks. Active group scores were significantly lower (P less than .0001) than placebo scores at each post-baseline time point for all indices, with the exception of plaque at 2 weeks. The 28 week active group scores were 21% lower than the placebo group for plaque, 25% lower for gingivitis, and 43% lower for bleeding on probing. No dental staining or taste alteration was reported in the active group. Three of 30 active group subjects exhibited minor soft tissue irritations that resolved spontaneously without discontinuation of product use. Results indicate that the test products showed good levels of safety and efficacy when administered in a combined use regimen for 6 months.


Clin Prev Dent 1990 Apr-May;12(1):13-7

Clinical evaluation of anticalculus dentifrices.

Kazmierczak M, Mather M, Ciancio S, Fischman S, Cancro L.

One hundred and eighty-seven patients participated in a six-month study to evaluate the calculus-inhibiting effect of a zinc citrate dentifrice compared to Crest Tartar Control and a placebo, Crest Regular. The findings demonstrate a statistically significant calculus prevention benefit over Crest Regular for both Crest Tartar Control and a 2% zinc citrate/silica product. Compared to the control, the zinc citrate product reduced calculus formation by 32.3%, and Crest Tartar Control reduced it by 21.4%. These findings also demonstrate no statistically significant difference in stain or soft tissue status among the three dentifrices. All products were found to be safe to oral tissues and acceptable for taste.

J La State Med Soc 1989 Sep;141(9):9-11

Disorders of taste.

Rareshide E, Amedee RG.

At least 2 million Americans suffer with chemosensory dysfunction or disorders of taste and smell. In addition to the obvious aesthetic deprivation, loss of taste may affect an individual’s health and psychosocial situation. Most taste disorders are associated with antecedent upper respiratory infection, trauma, or allergic rhinitis, or have an idiopathic etiology. They may reflect underlying neoplastic, neurologic, endocrine, infectious, or nutritional disturbances; only 1% of these patients have a functional disorder. Evaluation consists of a history and physical, followed by a screening test battery searching for any of the treatable etiologies. One third of patients will respond to exogenous zinc therapy after a treatment period of 2 to 4 months. The remainder must rely on supportive measures such as additives, flavor enhancers, and rinses.

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Start the New Year with a Bang, Not with Bad Breath

Monday, December 31st, 2007


Happy New Year! Most of us will be starting the year with a party, singing Auld Lang Syne whiletoasting and drinking to our heart’s content.New Year’s Eve parties usually mark the end of the year past and the beginning of the coming year, and alcohol is a staple presence in these parties. It is good to keep everything in moderation — you would want to remember that party, and not have the party remember you for the wrong reasons, right?It is still possible to have great fun without losing consciousness and proper judgment. Make sure that you are sober enough to drive when you do go home, or have a sober person drive you home.

One thing that you also have to be aware of is your breath. Alcohol consumption causes bad breath, something that you wouldn’t want to have in any party.

Alcohol is one of the top bad breath instigators — just next to cigarettes. It is a DESSICANT, or drying agent that makes the anaerobic bacteria in your mouth go crazy and party along with those smelly VSC’s or Volatile Sulfur compounds. You are starting the Year of the Rat, not the year of the Dragon Breath! As you know from information in this website and possibly your own personal problem, the dryer your mouth gets – the worse your breath gets.

Here’s how much alcohol (in Percentage and Proof) is contained in the leading products below:

Product

% Alcohol

As Proof

Other “BAD” Ingredients

Jack Daniels Bourbon

43%

86

bad breath and halitosis

Amaretto Liqueur

28%

56

bad breath and halitosis

Wine – Chardonnay

12.5%

25

bad breath and halitosis

Wine – Merlot

11.5%

23

bad breath and halitosis

Beer

3

6

bad breath and halitosis

TheraBreath

0%

0

bad breath and halitosis

The most common drying agent in food is Alcohol. Alcohol of course is the basis of all “adult” beverages such as Beer, Wine, and Hard liquor. It is used quite often in laboratories to “dry out” hard to reach areas in test tubes and beakers. It is also used, unfortunately in mouthwash, where it only makes the problem worse. If you’re planning to gargle with the same old alcohol-based mouthwash just right before going to that party, or after, before you drive, stop right there.

Your current store bought mouthwash contains ALCOHOL that dries your mouth and SWEETENER that actually feeds the smelly bacteria in your mouth.

That burning sensation you get from regular mouthwash doesn’t kill the bacteria, it just irritates your mouth. We’ll show what WILL do the job quickly and effectively without irritation.

Commercial products are based on outdated theories—That alcohol can stop these problems. In fact, alcohol-based mouthwash may create poor oral health, because it dries out the mouth which in turn causes an increase of dangerous Volatile Sulfur Compounds.

Just a tiny amount of alcohol can make your mouth dry instantly. As we already know, a dry mouth mimics an anaerobic (low oxygen) environment. Now, you’ve already learned what happens when the mouth is dry – it’s a perfect environment for the anaerobes to multiply and create more bad breath! Those strong mediciny or minty tastes are actually put into the mouthwash to mask bad breath – not get rid of it! (By the way, the leading mouthwash contains 27% alcohol – that’s more than a six pack of beer, and believe me, the beer tastes better!) And another interesting point – why do they make their mouthwash blue, green, or brown? What does color have to do with getting rid of bad breath?The answer, is, nothing.

Dr. Katz has created the mouthwash that addresses the root of the bad breath problem.Therabreath mouthwash does not contain alcohol and is the best solution to getting rid of bad breath before and after alcohol intake. It contains aloe vera which is good for gum health, does not contain saccharin (a sugar that feeds the bacteria), and does not leave a stinging feeling in the mouth – falsely believed by many as a sign of great breath. Gargling with alcoholic mouthwash after drinking alcohol is like swallowing ice in a snowy, cold day – it doesn’t make sense. You are merely aggravating the drying effects of the alcohol you drank.

One thing you must also avoid aside from alcohol-based mouthwash is breath mints or gum that are sugar-based. A common “solution” to situational bad breath is to pop a sugar-based breath mint or sugar-based gum. Although you may have a cinnamon-like taste in your mouth, what you’ve really just done is made your bad breath problem MUCH worse. Let me explain:

During your party dinner, you introduced two ‘triggers’ to your mouth (protein and alcohol) that weren’t previously there and made your particular oral environment very eager to begin creating those foul-smelling VSC’s.

Then after dinner, by sucking on that mint, you actually gave those bacteria a food source they LOVE (sugar) to help along the VSC production. Yes, it’s true you TASTE cinnamon or mint, but that’s only a temporary cover up and what people actually SMELL is usually a lot worse.

Dr. Katz has invented a breath mint that really does it job. It’s called Zox — The First Breath Mint To Actually NEUTRALIZE Bad Breath Production.

Dr. Katz created ZOX because he wanted to address the fact that almost all the other ‘breath mints’ on the market DO NOT take into account the principles of halitosis prevention that he’s been studying for the last 10 years. Most of them are created to TASTE GOOD and that’s about it. ZOX was created based on the same clinically proven Zinc/Oxygen/Xylitol principles used by the rest of the TheraBreath product line. It is literally bad breath prevention science packed into a roll of breath mints.

ZOX has no sugar – your breath mint should NEVER have sugar in it. ZOX uses xylitol which is a natural sweetener and has also been proven to have tremendous anti-decay properties.

Dr. Katz also has sugar-free gum alteranatives – Therabreath gum, “French Kiss” (a cinammon flavored gum used in Hollywood) and “Guy” a gum created especially for guys.

So eat, drink, and be merry, but don’t forget to be conscious of your breath.Check out the www.therabreath.com to find the best product that will enable you to enjoy the New Year’s eve festivities (and the entire year to come) without bad breath worries. Therabreath is also available in select stores – please check out the store locator for the location nearest you.

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Zinc in TheraBreath PLUS Mouthwash

Monday, September 10th, 2007

Zinc in TheraBreath PLUS Mouthwash

The scientific studies which follow will help explain why TheraBreath PLUS Oral Rinse, in addition to a higher concentration of OXYD-8, also contains Zinc Gluconate. Briefly, science has shown that adding zinc gluconate helps to eliminate sour/bitter/metallic tastes and also aids in reducing tartar buildup. The stabilized chlorine dioxide component (OXYD-8) in TheraBreath PLUS Oral Rinse is utilized to eliminate oral malodor, while Tea Tree Oil assists as a natural anti-microbial.


Biofactors 2000;12(1-4):65-70

Zinc deficiency and taste dysfunction; contribution of carbonic anhydrase, a zinc-metalloenzyme, to normal taste sensation.

by Komai M, Goto T, Suzuki H, Takeda T, Furukawa Y.

Division of Life Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan. mkomai@biochem.tohoku.ac.jp

The present study was designed to clarify the effect of zinc deficiency on sodium chloride preference, the lingual trigeminal and taste nerves transduction, and carbonic anhydrase (CA) activity of the tongue surface and salivary gland. Male SD rats, 4 weeks old, were divided into four groups, and fed zinc-deficient (Zn-Def), low-zinc (Low-Zn), and zinc-sufficient diets with free access (Zn-Suf) and pair-feeding (Pair-fed). After taking part in the preference tests for 42 days, the rats were provided for the chorda tympani and lingual trigeminal nerves recordings, then finally sacrificed and the tongue and submandibular gland excised to measure CA activity. Sodium chloride preference increased only after 4 days of the feeding of zinc-deficient and low-zinc diets, which means that the taste abnormality appears abruptly in zinc deficieny and even though in marginal zinc deficiency. Reduced CA activities of the taste-related tissues in zinc-deficient group paralleled well with the decreased taste and lingual trigeminal nerves sensitivities.


Effect of Different Mouthrinses on Morning Breath.

by van Steenberghe D, Avontroodt P, Peeters W, Pauwels M, Coucke W, Lijnen A, Quirynen M.

Department of Periodontology, Oral Pathology and Maxillo-Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Belgium.

BACKGROUND: Morning breath odor is an often-encountered complaint. This double-blind, crossover, randomized study aimed to examine the bad breath-inhibiting effect of 3 commercially available mouthrinses on morning halitosis during an experimental period of 12 days without mechanical plaque control.

METHODS: Twelve medical students with a healthy periodontium refrained from all means of mechanical plaque control during 3 experimental periods of 12 days (with intervening washout periods of at least 3 weeks). A professional oral cleaning preceded each period. During each experimental period, as the only oral hygiene measure allowed, the students rinsed twice a day with one of the following formulations in a randomized order: CHX-Alc (a 0.2% chlorhexidine [CHX] solution); CHX-NaF (CHX 0.12% plus sodium fluoride 0.05%); or CHX-CPC-Zn (CHX 0.05% plus cetylpyridinium chloride 0.05% plus zinc lactate 0.14%).

After 12 days, morning breath was scored via volatile sulfur compound (VSC) level measurements of the mouth air and organoleptic ratings of the mouth air, the expired air, and a scraping of the tongue coating. At the 12-day visit, a questionnaire (subjective ratings) was completed and samples taken from both the tongue coating and the saliva for anaerobic and aerobic culturing and vitality staining. The de novo supragingival plaque formation was also recorded. All parameters were correlated with the baseline registrations.

RESULTS: Although oral hygiene during the 3 experimental periods was limited to oral rinses, bad breath parameters systematically improved, with the exception of a slight increase in VSC levels while using CHX-Alc, a finding which was associated with the direct influence of the CHX on the sulfide monitor. The oral microbial load after the use of CHX-NaF remained unchanged, while for the CHX-Alc and CHX-CPC-Zn, significant reductions in both aerobic and anaerobic colony forming units (CFU)/ml were noticed in comparison with baseline data for both tongue coating and saliva samples. The composition of microflora, on the other hand, did not reveal significant changes. The supragingival plaque formation was inhibited, in descending order, by CHX-Alc, CHX-CPC-Zn, and CHX-NaF. The subjective scores for the rinses indicated a higher appreciation for CHX-CPC-Alc and CHX-NaF because of a better taste and fewer side effects. CONCLUSIONS: The results of this study demonstrate that morning halitosis can be successfully reduced via daily use of mouthrinses. CHX-Alc and CHX-CPC-Zn mouthrinses result in a significant reduction of the microbial load of tongue and saliva.

Publication Types:
· Clinical Trial
· Randomized Controlled Trial


PMID: 11577950 [PubMed – indexed for MEDLINE]

J Clin Periodontol 1996 May;23(5):465-70

The effect of mouth rinses containing zinc and triclosan on plaque accumulation, development of gingivitis and formation of calculus in a 28-week clinical test.

by Schaeken MJ, Van der Hoeven JS, Saxton CA, Cummins D.

Department of Periodontology and Preventive Dentistry, University of Nijmegan, The Netherlands.

Experimental mouthrinses containing 0.4% zinc sulphate and 0.15% triclosan, which differed in base formulations were compared to a commercially available non-active control mouthrinse. Following baseline clinical examinations for plaque, gingival bleeding and calculus, the volunteers were provided with a dental prophylaxis and given oral hygiene instruction, stratified into 3 groups and given 1 of 3 mouthrinses.

Further clinical assessments were performed after 4, 16 and 28 weeks. Salivary mutans streptococci were also monitored during the study. At 4 weeks, plaque and calculus scores in all groups were low compared to baseline. During the remainder of the study, these improvements were not maintained and both plaque and calculus levels increased in all groups. Plaque was significantly lower (P < 0.05) than in the control at all time points. Calculus was significantly lower (P < 0.05) than in the control at all time points. Calculus was significantly lower at week 28 for experimental mouthrinse group 2. Gingival bleeding also decreased in the initial 4 weeks but increased thereafter in the control group. In contrast, gingival bleeding was significantly (P < 0.05) lower in the two experimental groups than in the control group. No significant changes in mutans streptococci were observed.


Ann Pharmacother 1996 Feb;30(2):186-7
Zinc Deficiency and Taste Disorders.

by Heyneman CA.

Idaho Drug Information Center, Idaho State University, Pocatello 83209, USA.

Elemental zinc supplementation in daily dosages of 25-100 mg po appears to be an efficacious treatment for taste dysfunction secondary to zinc depletion. Insufficient evidence is available to determine the efficacy of zinc supplementation for the treatment of hypogeusia or dysgeusia secondary to drug therapy or medical conditions that do not involve low serum zinc concentrations.


Ther Umsch 1995 Nov;52(11):732-7

[Article in German] Huttenbrink KB.

Klinik und Poliklinik fur Hals-Nasen-Ohren-Heilkunde der Medizinischen Fakultat Carl Gustav Carus, Technischen Universitat Dresden.

Disorders of olfaction and taste are infrequent, but a complete loss of smell or taste reduces the quality of life significantly. The sensitivity of human olfaction is remarkable, even for specific stimuli: Just a few molecules are enough to induce the correct identification of sterilised and ultraheated milk.

Olfaction and taste are called ‘chemical senses’ because in both cases the adequate stimulus consists of molecules that bind to receptors of the sensory cells. The perceptions of smell and taste are often combined. Taste differentiates only four qualities: sweet, sour, salty, and bitter. The typical flavor of food or drink is detected by olfaction. Disturbances of olfaction can be due to respiratory disorders such as nasal polyps, a deviation of the nasal septum or chronic sinusitis. Such conditions can reduce airflow through the olfactory cleft at the roof of the nasal cavity. They can be corrected by modern endoscopic surgery of the nose.

Epithelial disorders involving the sensory cells are most often caused by viral infections (influenza-anosmia) or toxic destruction of the sensory epithelium (solvents or gases). Epithelial disorders can be cured only rarely by any treatment. Corticosteroids, zinc, and vitamin A are tried frequently. Neural disorders occur after frontobasal trauma and during neurological diseases such as Parkinson’s or Alzheimer’s disease. Disorders of olfaction can be an early sign of such neurological diseases and sophisticated examination of this sense can contribute to their early diagnosis. However, no specific treatments have yet been identified. Disorders of taste can be due to toxic, chemical or inflammatory damage to the sensory cells of the tongue.


Indian J Physiol Pharmacol 1993 Oct;37(4):318-22

Zinc Taste Test in Pregnant Women and its Correlation with Serum Zinc Level.

by Garg HK, Singal KC, Arshad Z.

Department of Pharmacology, J. N. Medical College, A.M.U., Aligarh.

Pregnant women in different trimesters of pregnancy were divided into control (n = 58) and study (n = 104) groups. Study group subjects were given 45 mg zinc/p.o./day as 200 mg ‘zinc sulphate tablets from the day of reporting till term. Body zinc status was clinically assessed by ‘zinc taste test’. Blood samples were drawn at the same time and serum zinc levels measured. Zinc taste test scores decreased with advancement of pregnancy (P < 0.05) and increased significantly following zinc administration (P < 0.05).

Serum zinc level declined significantly with advancement of pregnancy (P < 0.001). Following zinc administration, serum zinc level increased significantly (P < 0.001). Accuracy of zinc taste test in individual cases ranged between 70 and 100 percent. On the whole, zinc taste test was well correlated with serum zinc level, and provides a fair idea of zinc deficiency.


Nutrition 1993 May-Jun;9(3):218-24

Zinc deficiency in elderly patients.

by AS, Fitzgerald JT, Hess JW, Kaplan J, Pelen F, Dardenne M. – Department of Internal Medicine, Wayne State University School of Medicine, Detroit, MI.

Zinc is needed for growth and development, DNA synthesis, neurosensory functions, and cell-mediated immunity. Although zinc intake is reduced in elderly people, its deficiency and effects on cell-mediated immunity of the elderly have not been established. Subjects enrolled in “A Model Health Promotion and Intervention Program for Urban Middle Aged and Elderly Americans” were assessed for nutrition and zinc status. One hundred eighty healthy subjects were randomly selected for the study. Their mean dietary zinc intake was 9.06 mg/day, whereas the recommended dietary allowance is 15 mg/day. Plasma zinc was normal, but zinc in granulocytes and lymphocytes were decreased compared with younger control subjects. Of 118 elderly subjects in whom zinc levels in both granulocytes and lymphocytes were available, 36 had deficient levels.

Plasma copper was increased, and interleukin 1 (IL-1) production was significantly decreased. Reduced response to the skin-test antigen panel and decreased taste acuity were observed. Thirteen elderly zinc-deficient subjects were supplemented with zinc, and various variables were assessed before and after zinc supplementation. Zinc supplementation corrected zinc deficiency and normalized plasma copper levels. Serum thymulin activity, IL-1 production, and lymphocyte ecto-5′-nucleotidase increased significantly after supplementation. Improvement in response to skin-test antigens and taste acuity was observed after zinc supplementation. A mild zinc deficiency appears to be a significant clinical problem in free-living elderly people.


Arch Otolaryngol Head Neck Surg 1991 May;117(5):519-28

Smell and taste disorders, a study of 750 patients from the University of Pennsylvania Smell and Taste Center.

Deems DA, Doty RL, Settle RG, Moore-Gillon V, Shaman P, Mester AF, Kimmelman CP, Brightman VJ, Snow JB Jr. – Department of Otorhinolaryngology and Human Communication, School of Medicine, University of Pennsylvania, Philadelphia.

Smell and taste disorders are common in the general population, yet little is known about their nature or cause. This article describes a study of 750 patients with complaints of abnormal smell or taste perception from the University of Pennsylvania Smell and Taste Center, Philadelphia. Major findings suggest that: chemosensory dysfunction influences quality of life; complaints of taste loss usually reflect loss of smell function; upper respiratory infection, head trauma, and chronic nasal and paranasal sinus disease are the most common causes of the diminution of the sense of smell, with head trauma having the greatest loss; depression frequently accompanies chemosensory distortion; low body weight accompanies burning mouth syndrome; estrogens protect against loss of the sense of smell in postmenopausal women; zinc therapy may provide no benefit to patients with chemosensory dysfunction; and thyroid hormone function is associated with oral sensory distortion. The findings are discussed in relation to management of patients with chemosensory disturbances.


J Periodontol 1990 Jun;61(6):352-8

Clinical efficacy of a dentifrice and oral rinse containing sanguinaria extract and zinc chloride during 6 months of use.

Harper DS, Mueller LJ, Fine JB, Gordon J, Laster LL. – Fairleigh-Dickinson University, Oral Health Research Center, Hackensack, NJ.

The efficacy of combined use of toothpaste and oral rinse containing sanguinaria extract and zinc chloride was compared to placebo products in a 6-month clinical trial. Sixty subjects with moderate levels of plaque and gingivitis were randomly assigned to active and placebo groups. Noninvasive measures of plaque and gingivitis were assessed at baseline and at 2, 6, 8, 14, 20, and 28 weeks. Bleeding on probing was measured at baseline and 6, 14, and 28 weeks. Active group scores were significantly lower (P less than .0001) than placebo scores at each post-baseline time point for all indices, with the exception of plaque at 2 weeks. The 28 week active group scores were 21% lower than the placebo group for plaque, 25% lower for gingivitis, and 43% lower for bleeding on probing. No dental staining or taste alteration was reported in the active group. Three of 30 active group subjects exhibited minor soft tissue irritations that resolved spontaneously without discontinuation of product use. Results indicate that the test products showed good levels of safety and efficacy when administered in a combined use regimen for 6 months.


Clin Prev Dent 1990 Apr-May;12(1):13-7

Clinical evaluation of anticalculus dentifrices.

Kazmierczak M, Mather M, Ciancio S, Fischman S, Cancro L.

One hundred and eighty-seven patients participated in a six-month study to evaluate the calculus-inhibiting effect of a zinc citrate dentifrice compared to Crest Tartar Control and a placebo, Crest Regular. The findings demonstrate a statistically significant calculus prevention benefit over Crest Regular for both Crest Tartar Control and a 2% zinc citrate/silica product. Compared to the control, the zinc citrate product reduced calculus formation by 32.3%, and Crest Tartar Control reduced it by 21.4%. These findings also demonstrate no statistically significant difference in stain or soft tissue status among the three dentifrices. All products were found to be safe to oral tissues and acceptable for taste.

J La State Med Soc 1989 Sep;141(9):9-11

Disorders of taste.

Rareshide E, Amedee RG.

At least 2 million Americans suffer with chemosensory dysfunction or disorders of taste and smell. In addition to the obvious aesthetic deprivation, loss of taste may affect an individual’s health and psychosocial situation. Most taste disorders are associated with antecedent upper respiratory infection, trauma, or allergic rhinitis, or have an idiopathic etiology. They may reflect underlying neoplastic, neurologic, endocrine, infectious, or nutritional disturbances; only 1% of these patients have a functional disorder. Evaluation consists of a history and physical, followed by a screening test battery searching for any of the treatable etiologies. One third of patients will respond to exogenous zinc therapy after a treatment period of 2 to 4 months. The remainder must rely on supportive measures such as additives, flavor enhancers, and rinses.

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